How CBD differs from THC


Research by the World Health Organization has suggested CBD has low toxicity and no significant effects unless extremely high doses are administered

Over the years, there has been confusion about the differences between CBD and THC. On a chemical level, there are far more similarities than differences between these two naturally occurring compounds, yet the human body reacts to them very differently. Many people are also unaware that CBD is more prevalent in hemp, while THC is found in significantly higher concentrations in cannabis plants.

To dispel the confusion, Cannalogica has investigated the key scientific and medical differences between CBD and THC. The answers might just surprise you…


The Chemicals
Between Us

On paper, you’d be forgiven for assuming there are no differences between CBD and THC, known scientifically as cannabidiol and delta-9-tetrahydrocannabinol. Both are comprised of 21 carbon atoms, 30 hydrogen atoms and two oxygen atoms. Yet there are significant variances in the way these atoms bond with each other, which in turn ensure these two cannabinoids react differently in the human body.


All vertebrates have neurotransmitters known as endocannabinoids in their bodies, which help to regulate everything from appetite to mood. In humans, the CB1 and CB2 cannabinoid receptors are particularly important. CBD is more likely to bind to CB2 receptors, which govern aspects of our peripheral nervous system. That makes CBD-infused products well-suited for topical application. Conversely, CB1 receptors (with their THC affinity) are commonly found in our brains and spinal cords. This explains why THC has a rapid and often significant effect on memory and cognition.

There are also differences in the plants grown for THC and CBD. Hemp is a strain of cannabis plant containing less than 0.3 per cent THC1, meaning it’s rarely psychoactive. The benefits of hemp have been known for centuries, and because it only contains small amounts of THC, it’s grown industrially and used for materials as diverse as fiber, paper and plastic substitutes. Hemp can be burned for fuel and developed into soybean-style foodstuffs and flour, while hemp seed oil is used to manufacture varnishes and lubricating oils, paints and inks.


The psychoactive properties of THC are widely recognized and well-documented, whereas CBD doesn’t produce the same effects. Research by the World Health Organization has suggested CBD has low toxicity and no significant effects unless extremely high doses are administered, while the only prospect of side effects comes from interactions with other medications.

Cannalogica exclusively uses hemp plants to extract CBD for our range of skincare and beauty products. For instance, it’s incorporated into our moisturizer alongside other natural plant extracts like apricot kernel oil, lemongrass leaf oil and shea nut butter. This balance of ingredients has been carefully formulated through laboratory testing by a team of experts, to create a delicate and aromatic product which can moisturize and soften the skin.

The differences between CBD and THC may seem modest on paper, but they are worlds apart in how they interact with our bodies. Indeed, Cannalogica is proud to be one of the first cosmetics and beauty brands to incorporate CBD into our products. You can find out more about our product range by clicking the button below.

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